3FFI: HIV-1 RT with pyridone non-nucleoside inhibitor

PDB ID: 3FFIDownload
MMDB ID: 78708
PDB Deposition Date: 2008/12/3
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3FFI: dimeric; determined by author and by software (PISA)
Molecular Components in 3FFI
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
RT P51
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-chloro-5-({6-[2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-3-(dimethylamino)-2-oxo-1,2-dihydropyridin-4-yl}oxy)benzonitrile3-chloro-5-({6-[2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-3-(dimethylamino)-2-oxo-1,2-dihydropyridin-4-yl}oxy)benzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303