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3F0B:
Staphylococcus Aureus Dihydrofolate Reductase Complexed With Nadph And 2,4-diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6- Methylpyrimidine
PDB ID:
3F0B
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MMDB ID:
70380
PDB Deposition Date:
2008/10/24
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Staphylococcus aureus RF122
Similar Structures:
VAST+
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Biological Unit for 3F0B: monomeric; determined by author and by software (PISA)
Molecular Components in 3F0B
Label
Count
Molecule
Protein (1 molecule)
X
1
Trimethoprim-sensitive Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
Nadph Dihydro-Nicotinamide-Adenine-Dinucleotide Phosphate
2
1
5-[(3r)-3-(5-Methoxybiphenyl-3-Yl)but-1-Yn-1-Yl]-6-Methylpyrimidine-2,4-Diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303