3E4A: Human IDE-inhibitor complex at 2.6 angstrom resolution

PDB ID: 3E4ADownload
MMDB ID: 72752
PDB Deposition Date: 2008/8/11
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3E4A: dimeric; determined by author and by software (PISA)
Molecular Components in 3E4A
Label Count Molecule
Proteins (2 molecules)
1
Insulin-degrading Enzyme
Molecule annotation
1
Hydroxamate Peptide II1
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC IONZINC ION
2
1
N~2~-[(2R)-4-(HYDROXYAMINO)-2-(2-NAPHTHYLMETHYL)-4-OXOBUTANOYL]-L-ARGINYLGLYCYLGLYCINAMIDEN~2~-[(2R)-4-(HYDROXYAMINO)-2-(2-NAPHTHYLMETHYL)-4-OXOBUTANOYL]-L-ARGINYLGLYCYLGLYCINAMIDE
3
2
1,4-DIETHYLENE DIOXIDE1,4-DIETHYLENE DIOXIDE
4
8
ACETIC ACIDACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303