3DDP: Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor CR8

PDB ID: 3DDPDownload
MMDB ID: 255456
PDB Deposition Date: 2008/6/6
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3DDP: dimeric; determined by author and by software (PISA)
Molecular Components in 3DDP
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
Molecule annotation
1
Cyclin-a2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303