3COH: Crystal Structure Of Aurora-A In Complex With A Pentacyclic Inhibitor

PDB ID: 3COHDownload
MMDB ID: 69685
PDB Deposition Date: 2008/3/28
Updated in MMDB: 2009/07
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3COH: monomeric; determined by author and by software (PISA)
Molecular Components in 3COH
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 6
(Gene symbol: AURKA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-Ethyl-3,10,10-Trimethyl-4,5,6,8,10,12-Hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-B]pyrrolo[2,3-F]indol-9(1h)-One8-ethyl-2,5,6,12-tetrahydro-3,10,10-trimethyl-9-oxo-pyrazolo[4'3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303