3CO9: Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

PDB ID: 3CO9Download
MMDB ID: 69530
PDB Deposition Date: 2008/3/27
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3CO9: monomeric; determined by author and by software (PISA)
Molecular Components in 3CO9
Label Count Molecule
Protein (1 molecule)
1
RNA-directed RNA Polymerase
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydropyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7 -yl}methanesulfonamideN-{3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydropyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7 -yl}methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303