3C4C: B-Raf Kinase in Complex with PLX4720

PDB ID: 3C4CDownload
MMDB ID: 62742
PDB Deposition Date: 2008/1/29
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Biological Unit for 3C4C: monomeric; determined by author and by software (PISA)
Molecular Components in 3C4C
Label Count Molecule
Protein (1 molecule)
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: BRAF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamideN-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303