2ZQ9: Cephalothin acyl-intermediate structure of class a beta-lactamase Toho-1 E166A/R274N/R276N triple mutant

PDB ID: 2ZQ9Download
MMDB ID: 75572
PDB Deposition Date: 2008/8/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.07  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZQ9: monomeric; determined by author and by software (PISA)
Molecular Components in 2ZQ9
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase Toho-1
(Gene symbol: bla)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
SULFATE IONSULFATE ION
2
1
5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
3
1
CEPHALOTHINCEPHALOTHIN
4
1
THIOPHENEACETIC ACIDTHIOPHENEACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303