NCBI
National Center for
Biotechnology Information
Search
2Z54:
The Influence of I47A Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir
PDB ID:
2Z54
Download
MMDB ID:
65219
PDB Deposition Date:
2007/6/28
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
2.31 Å
Source Organism:
Human immunodeficiency virus type 1 (BH5 ISOLATE)
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2Z54: dimeric; determined by author and by software (PISA)
Molecular Components in 2Z54
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Hiv-1 Protease
Chemicals and Non-standard biopolymers (3 molecules)
1
2
BETA-MERCAPTOETHANOL
2
1
N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303