2YEF: HSP90 inhibitors and drugs from fragment and virtual screening

PDB ID: 2YEFDownload
MMDB ID: 91732
PDB Deposition Date: 2011/3/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 2YEF: monomeric; determined by author and by software (PISA)
Molecular Components in 2YEF
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303