2YAU: X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin

PDB ID: 2YAUDownload
MMDB ID: 96284
PDB Deposition Date: 2011/2/24
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2YAU: dimeric; determined by author and by software (PISA)
Molecular Components in 2YAU
Label Count Molecule
Proteins (2 molecules)
2
Trypanothione Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
GOLD IONGOLD ION
4
2
2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose
5
2
CHLORIDE IONCHLORIDE ION
6
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303