2Y6O: Crystal structure of EphA4 kinase domain in complex with Dasatinib

PDB ID: 2Y6ODownload
MMDB ID: 94713
PDB Deposition Date: 2011/1/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.543  Å
Source Organism:
Similar Structures:
Biological Unit for 2Y6O: monomeric; determined by author and by software (PISA)
Molecular Components in 2Y6O
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-a Receptor 4
(Gene symbol: Epha4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDEN-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303