2Y3Y: Holo-Ni(Ii) Hpnikr Is A Symmetric Tetramer Containing Four Canonic Square-Planar Ni(Ii) Ions At Physiological Ph

The crystal structure of Helicobacter pylori holo-NikR, a Ni(2+)-dependent transcription factor, determined at pH 7.3, shows four square-planar nickel-binding sites, involving one cysteinate and three histidine ligands. This observation reconciles previous inconsistencies among calorimetric data, structural information at non-physiological pH, and computational studies.
PDB ID: 2Y3YDownload
MMDB ID: 92687
PDB Deposition Date: 2011/1/4
Updated in MMDB: 2011/08
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Helicobacter pylori G27
Similar Structures:
Biological Unit for 2Y3Y: tetrameric; determined by author and by software (PISA)
Molecular Components in 2Y3Y
Label Count Molecule
Proteins (4 molecules)
Putative Nickel-responsive Regulator
Molecule annotation
Chemicals (4 molecules)
* Click molecule labels to explore molecular sequence information.

Citing MMDB