2Y1W: CRYSTAL STRUCTURE OF COACTIVATOR ASSOCIATED ARGININE METHYLTRANSFERASE 1 (CARM1) IN COMPLEX WITH SINEFUNGIN AND INDOLE INHIBITOR

PDB ID: 2Y1WDownload
MMDB ID: 89327
PDB Deposition Date: 2010/12/10
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2Y1W: tetrameric; determined by author and by software (PISA)
Molecular Components in 2Y1W
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: CARM1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
SINEFUNGINSINEFUNGIN
2
4
2-{4-[3-FLUORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL] PIPERIDIN-1-YL}-N-METHYLETHANAMINE2-{4-[3-FLUORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL] PIPERIDIN-1-YL}-N-METHYLETHANAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303