2XXI: Crystal structure of 1-((4-(3-(trifluoromethyl)-6,7-dihydropyrano(4,3- c(pyrazol-1(4H)-yl)phenyl)methyl)-2-pyrrolidinone in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 1.6A resolution

PDB ID: 2XXIDownload
MMDB ID: 89643
PDB Deposition Date: 2010/11/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2XXI: dimeric; determined by author and by software (PISA)
Molecular Components in 2XXI
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Receptor 2
(Gene symbol: Gria2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
3
GLUTAMIC ACIDGLUTAMIC ACID
2
2
1-({4-[3-(TRIFLUOROMETHYL)-6,7-DIHYDROPYRANO[4,3-C]PYRAZOL-1(4H)-YL]PHENYL}METHYL)-2-PYRROLIDINONE1-({4-[3-(TRIFLUOROMETHYL)-6,7-DIHYDROPYRANO[4,3-C]PYRAZOL-1(4H)-YL]PHENYL}METHYL)-2-PYRROLIDINONE
3
1
SULFATE IONSULFATE ION
4
3
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303