2XX8: Crystal structure of N,N-dimethyl-4-(3-(trifluoromethyl)-4,5,6,7- tetrahydro-1H-indazol-1-yl)benzamide in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 2.2A resolution

PDB ID: 2XX8Download
MMDB ID: 90094
PDB Deposition Date: 2010/11/9
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 2XX8: dimeric; determined by author and by software (PISA)
Molecular Components in 2XX8
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Receptor 2
(Gene symbol: Gria2)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
3
GLUTAMIC ACIDGLUTAMIC ACID
2
2
N,N-DIMETHYL-4-[3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]BENZAMIDEN,N-DIMETHYL-4-[3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]BENZAMIDE
3
1
SULFATE IONSULFATE ION
4
4
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303