2XX5: Macrolactone Inhibitor bound to HSP90 N-term

PDB ID: 2XX5Download
MMDB ID: 95005
PDB Deposition Date: 2010/11/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2XX5: dimeric; determined by author and by software (PISA)
Molecular Components in 2XX5
Label Count Molecule
Proteins (2 molecules)
2
Atp-dependent Molecular Chaperone Hsp82
(Gene symbol: HSP82)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(5E,10R)-N-BENZYL-13-CHLORO-14,16-DIHYDROXY-1,11-DIOXO-1,2,3,4,7,8,9,10,11,12-DECAHYDRO-2-BENZAZACYCLOTETRADECINE-10-CARBOXAMIDE(5E,10R)-N-BENZYL-13-CHLORO-14,16-DIHYDROXY-1,11-DIOXO-1,2,3,4,7,8,9,10,11,12-DECAHYDRO-2-BENZAZACYCLOTETRADECINE-10-CARBOXAMIDE
2
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303