2XK9: Structural analysis of checkpoint kinase 2 (Chk2) in complex with inhibitor PV1533

PDB ID: 2XK9Download
MMDB ID: 92084
PDB Deposition Date: 2010/7/7
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 2XK9: dimeric; determined by author and by software (PISA)
Molecular Components in 2XK9
Label Count Molecule
Proteins (2 molecules)
2
Checkpoint Kinase 2
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-{4-[(1E)-N-(N-hydroxycarbamimidoyl)ethanehydrazonoyl]phenyl}-7-nitro-1H-indole-2-carboxamideN-{4-[(1E)-N-(N-hydroxycarbamimidoyl)ethanehydrazonoyl]phenyl}-7-nitro-1H-indole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303