2XE0: Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

PDB ID: 2XE0Download
MMDB ID: 85127
PDB Deposition Date: 2010/5/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.31  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 2XE0: tetrameric; determined by author and by software (PISA)
Molecular Components in 2XE0
Label Count Molecule
Proteins (2 molecules)
1
I-crei V2v3 Variant
Molecule annotation
1
I-crei V2v3 Variant
Molecule annotation
Nucleotides(2 molecules)
1
24mer DNA
Molecule annotation
1
24mer DNA
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
ACETATE IONACETATE ION
2
1
S-1,2-PROPANEDIOLS-1,2-PROPANEDIOL
3
3
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303