2XDU: Structure of HSP90 with small molecule inhibitor bound

PDB ID: 2XDUDownload
MMDB ID: 84511
PDB Deposition Date: 2010/5/7
Updated in MMDB: 2010/09
Experimental Method:
x-ray diffraction
Resolution: 1.74  Å
Source Organism:
Similar Structures:
Biological Unit for 2XDU: monomeric; determined by software (PISA)
Molecular Components in 2XDU
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
PYRIMIDIN-2-AMINEPYRIMIDIN-2-AMINE
4
1
1-CHLORO-4-METHYLPHTHALAZINE1-CHLORO-4-METHYLPHTHALAZINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303