2XCT: The twinned 3.35A structure of S. aureus Gyrase complex with Ciprofloxacin and DNA

PDB ID: 2XCTDownload
MMDB ID: 84308
PDB Deposition Date: 2010/4/25
Updated in MMDB: 2010/08
Experimental Method:
x-ray diffraction
Resolution: 3.35  Å
Source Organism:
Staphylococcus aureus subsp. aureus N315▼
Similar Structures:
Biological Unit for 2XCT: hexameric; determined by author and by software (PISA)
Molecular Components in 2XCT
Label Count Molecule
Proteins (2 molecules)
2
DNA Gyrase Subunit B, DNA Gyrase Subunit a
Molecule annotation
Nucleotides(4 molecules)
1
5'-d(tp*gp*tp*gp*cp*gp*gp*t)-3'
Molecule annotation
1
5'-d(ap*gp*cp*cp*gp*tp*ap*g)-3'
Molecule annotation
1
5'-d(gp*tp*ap*cp*cp*cp*ap*cp*gp*gp*cp*t)-3'
Molecule annotation
1
5'-d(gp*tp*ap*cp*ap*cp*cp*gp*cp*ap*cp*a)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
MANGANESE (II) IONMANGANESE (II) ION
2
2
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303