2XCR: The 3.5A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase complexed with GSK299423 and DNA

PDB ID: 2XCRDownload
MMDB ID: 83787
PDB Deposition Date: 2010/4/25
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2XCR: tetrameric; determined by software (PISA)
Molecular Components in 2XCR
Label Count Molecule
Proteins (2 molecules)
2
DNA Gyrase Subunit B, DNA Gyrase Subunit a
Molecule annotation
Nucleotides(2 molecules)
2
5'-d(*5ua*gp*cp*cp*gp*tp*ap*gp*gp*gp*cp*cp*cp*tp*ap*cp*gp *gp*cp*tp)-3'
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303