2XCN: Crystal Structure Of Hcv Ns3 Protease With A Boronate Inhibitor

PDB ID: 2XCNDownload
MMDB ID: 82427
PDB Deposition Date: 2010/4/23
Updated in MMDB: 2010/06
Experimental Method:
x-ray diffraction
Resolution: 3.02  Å
Source Organism:
Similar Structures:
Biological Unit for 2XCN: tetrameric; determined by author and by software (PISA)
Molecular Components in 2XCN
Label Count Molecule
Proteins (4 molecules)
2
NS3 Protease
Molecule annotation
2
Ns4a
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
N-[(cyclopentyloxy)carbonyl]-3-methyl-l-valyl-(4r)-n-{(1r)-3-hydroxy-1-[hydroxy(oxido)boranyl]propyl}-4-(isoquinolin-1-yloxy)-l-prolinamideN-[(cyclopentyloxy)carbonyl]-3-methyl-l-valyl-(4r)-n-{(1r)-3-hydroxy-1-[hydroxy(oxido)boranyl]propyl}-4-(isoquinolin-1-yloxy)-l-prolinamide
2
2
Magnesium IonMagnesium Ion
3
2
Zinc IonZinc Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303