2XBA: Structure of Human Anaplastic Lymphoma Kinase in complex with PHA- E429

PDB ID: 2XBADownload
MMDB ID: 83586
PDB Deposition Date: 2010/4/8
Updated in MMDB: 2010/08
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 2XBA: monomeric; determined by author and by software (PISA)
Molecular Components in 2XBA
Label Count Molecule
Protein (1 molecule)
1
ALK Tyrosine Kinase Receptor
(Gene symbol: ALK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(2R)-2-hydroxy-2-phenylacetyl]-3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-1,6-dihydropyrrolo[3,4-c]pyrazol-5-ium5-[(2R)-2-hydroxy-2-phenylacetyl]-3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-1,6-dihydropyrrolo[3,4-c]pyrazol-5-ium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303