2X81: STRUCTURE OF AURORA A IN COMPLEX WITH MLN8054

PDB ID: 2X81Download
MMDB ID: 81803
PDB Deposition Date: 2010/3/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.91  Å
Source Organism:
Similar Structures:
Biological Unit for 2X81: monomeric; determined by author and by software (PISA)
Molecular Components in 2X81
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 6
(Gene symbol: AURKA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303