2WPU: Chaperoned ruthenium metallodrugs that recognize telomeric DNA

PDB ID: 2WPUDownload
MMDB ID: 85417
PDB Deposition Date: 2009/8/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.92  Å
Source Organism:
Similar Structures:
Biological Unit for 2WPU: tetrameric; determined by author and by software (PISA)
Molecular Components in 2WPU
Label Count Molecule
Proteins (4 molecules)
4
Streptavidin
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
(3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III)(3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III)
2
4
SULFATE IONSULFATE ION
3
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303