2WPB: Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2R,3R)-2,3,4- trihydroxy-N,N-dipropylbutanamide in space group P21 crystal form I

PDB ID: 2WPBDownload
MMDB ID: 84297
PDB Deposition Date: 2009/8/3
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 2WPB: tetrameric; determined by author and by software (PISA)
Molecular Components in 2WPB
Label Count Molecule
Proteins (4 molecules)
4
N-acetylneuraminate Lyase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
(2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE(2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303