2WM1: The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis

PDB ID: 2WM1Download
MMDB ID: 77756
PDB Deposition Date: 2009/6/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
Similar Structures:
Biological Unit for 2WM1: dimeric; determined by author and by software (PISA)
Molecular Components in 2WM1
Label Count Molecule
Proteins (2 molecules)
2
2-amino-3-carboxymuconate-6-semialdehyde Decarboxylase
(Gene symbol: ACMSD)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
1,3-DIHYDROXYACETONEPHOSPHATE1,3-DIHYDROXYACETONEPHOSPHATE
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303