2WK3: Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-42)

PDB ID: 2WK3Download
MMDB ID: 78245
PDB Deposition Date: 2009/6/5
Updated in MMDB: 2009/11
Experimental Method:
x-ray diffraction
Resolution: 2.59  Å
Source Organism:
Similar Structures:
Biological Unit for 2WK3: dimeric; determined by author and by software (PISA)
Molecular Components in 2WK3
Label Count Molecule
Proteins (2 molecules)
1
Insulin Degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
1
Beta-amyloid Protein 42
(Gene symbol: APP)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303