2WI4: Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone

PDB ID: 2WI4Download
MMDB ID: 75546
PDB Deposition Date: 2009/5/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2WI4: monomeric; determined by author and by software (PISA)
Molecular Components in 2WI4
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein, HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303