2W3K: Crystal Structure of FXa in complex with 4,4-disubstituted pyrrolidine-1,2-dicarboxamide inhibitor 1

PDB ID: 2W3KDownload
MMDB ID: 70638
PDB Deposition Date: 2008/11/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 2W3K: dimeric; determined by author and by software (PQS)
Molecular Components in 2W3K
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor X, Heavy Chain
(Gene symbol: F10)
Molecule annotation
1
Coagulation Factor X, Light Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide(2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303