2VWV: Ephb4 Kinase Domain Inhibitor Complex

Citation:
Abstract
A series of bis-anilinopyrimidines have been identified as potent inhibitors of the tyrosine kinase EphB4. Structural information from two alternative series identified from screening efforts was combined to identify the initial leads.
PDB ID: 2VWVDownload
MMDB ID: 65372
PDB Deposition Date: 2008/6/27
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2VWV: monomeric; determined by author and by software (PQS)
Molecular Components in 2VWV
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-b Receptor 4(Gene symbol: EPHB4)
Molecule annotation
Chemical (1 molecule)
1
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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