2VR4: Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure

PDB ID: 2VR4Download
MMDB ID: 239978
PDB Deposition Date: 2008/3/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2VR4: monomeric; determined by author and by software (PQS)
Molecular Components in 2VR4
Label Count Molecule
Protein (1 molecule)
1
Beta-mannosidase
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
1
(2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol(2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol
2
20
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
6
BROMIDE IONBROMIDE ION
4
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303