2UV2: Crystal Structure Of Human Ste20-Like Kinase Bound To 4-(4-(5- Cyclopropyl-1H-pyrazol-3-ylamino)-quinazolin-2-ylamino)-phenyl)- acetonitrile

PDB ID: 2UV2Download
MMDB ID: 239956
PDB Deposition Date: 2007/3/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2UV2: dimeric; determined by author and by software (PQS)
Molecular Components in 2UV2
Label Count Molecule
Proteins (2 molecules)
2
Ste20-like Serine-threonine Kinase
(Gene symbol: SLK)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
4
THIOCYANATE IONTHIOCYANATE ION
3
2
[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303