2TYS: CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES

PDB ID: 2TYSDownload
MMDB ID: 5822
PDB Deposition Date: 1997/1/8
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2TYS: tetrameric; determined by author
Molecular Components in 2TYS
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase
(Gene symbol: trpA)
Molecule annotation
2
Tryptophan Synthase
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
SODIUM IONSODIUM ION
2
2
[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303