2TSC: STRUCTURE, MULTIPLE SITE BINDING, AND SEGMENTAL ACCOMODATION IN THYMIDYLATE SYNTHASE ON BINDING D/UMP AND AN ANTI-FOLATE

PDB ID: 2TSCDownload
MMDB ID: 2965
PDB Deposition Date: 1991/7/3
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 2TSC: dimeric; determined by author and by software (PISA)
Molecular Components in 2TSC
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303