2R9F: Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide

PDB ID: 2R9FDownload
MMDB ID: 235010
PDB Deposition Date: 2007/9/12
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2R9F: monomeric; determined by author and by software (PISA)
Molecular Components in 2R9F
Label Count Molecule
Protein (1 molecule)
1
Calpain-1 Catalytic Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
CALCIUM IONCALCIUM ION
2
3
CHLORIDE IONCHLORIDE ION
3
1
benzyl [(1S)-1-{[(1S,2S)-1-ethyl-2-hydroxy-3-{[3-(4-methylpiperazin-1-yl)propyl]amino}-3-oxopropyl]carbamoyl}-3-methylbutyl]carbamatebenzyl [(1S)-1-{[(1S,2S)-1-ethyl-2-hydroxy-3-{[3-(4-methylpiperazin-1-yl)propyl]amino}-3-oxopropyl]carbamoyl}-3-methylbutyl]carbamate
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303