2Q8K: The Crystal Structure Of Ebp1

The ErbB-3 receptor binding protein (Ebp1) is a member of the proliferation-associated 2G4 (PA2G4) family implicated in regulation of cell growth and differentiation. Here, we report the crystal structure of the human Ebp1 at 1.6 A resolution. The protein has the conserved pita bread fold of methionine aminopeptidases, but without the characteristic enzymatic activity. Moreover, Ebp1 is known to interact with a number of proteins and RNAs involved in either transcription regulation or translation control. The structure provides insights in how Ebp1 discriminates between its different interaction partners.
PDB ID: 2Q8KDownload
MMDB ID: 59400
PDB Deposition Date: 2007/6/11
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2Q8K: monomeric; determined by author
Molecular Components in 2Q8K
Label Count Molecule
Protein (1 molecule)
Proliferation-associated Protein 2G4(Gene symbol: PA2G4)
Molecule annotation
Chemicals (7 molecules)
* Click molecule labels to explore molecular sequence information.

Citing MMDB