2O8C: human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair

PDB ID: 2O8CDownload
MMDB ID: 234977
PDB Deposition Date: 2006/12/12
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 3.37  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2O8C: tetrameric; determined by author
Molecular Components in 2O8C
Label Count Molecule
Proteins (2 molecules)
1
DNA Mismatch Repair Protein Msh2
Molecule annotation
1
DNA Mismatch Repair Protein Msh6
Molecule annotation
Nucleotides(2 molecules)
1
5'-d(*gp*ap*ap*cp*cp*gp*cp*(6og)p*cp*gp*cp*tp*ap*gp*g)-3'
Molecule annotation
1
5'-d(*cp*cp*tp*ap*gp*cp*gp*tp*gp*cp*gp*gp*tp*tp*c)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303