2NSX: Structure of acid-beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease

PDB ID: 2NSXDownload
MMDB ID: 43503
PDB Deposition Date: 2006/11/6
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 2NSX: monomeric; determined by author
Molecular Components in 2NSX
Label Count Molecule
Protein (1 molecule)
1
Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
SULFATE IONSULFATE ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303