2KY7: NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate

PDB ID: 2KY7Download
MMDB ID: 82413
PDB Deposition Date: 2010/5/17
Updated in MMDB: 2010/07
Experimental Method:
solution nmr
Source Organism:
Biological Unit for 2KY7: dimeric; determined by software (PISA)
Molecular Components in 2KY7
Label Count Molecule
Nucleotides(2 molecules)
2
5'-d(*ap*ap*cp*ap*ap*tp*tp*gp*tp*t)-3'
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303