2JH8: The Structure Of Bluetongue Virus Vp4 Reveals A Multifunctional Rna-capping Production-line

Citation:
Abstract
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
PDB ID: 2JH8Download
MMDB ID: 45821
PDB Deposition Date: 2007/2/21
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 3.22  Å
Similar Structures:
Biological Unit for 2JH8: monomeric; determined by author and by software (PQS)
Molecular Components in 2JH8
Label Count Molecule
Protein (1 molecule)
1
VP4 Core Protein(Gene symbol: BTVs4gp1)
Molecule annotation
Chemicals (3 molecules)
1
1
2
2
* Click molecule labels to explore molecular sequence information.

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