2J2I: Crystal Structure of the humab PIM1 in complex with LY333531

PDB ID: 2J2IDownload
MMDB ID: 77910
PDB Deposition Date: 2006/8/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2J2I: monomeric; determined by author and by software (PQS)
Molecular Components in 2J2I
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SULFATE IONSULFATE ION
2
1
(9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H][1,4,13]OXADIA ZACYCLOHEXADECINE-18,20-DIONE(9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H][1,4,13]OXADIA ZACYCLOHEXADECINE-18,20-DIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303