2IW8: STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR

PDB ID: 2IW8Download
MMDB ID: 239943
PDB Deposition Date: 2006/6/27
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2IW8: dimeric; determined by software (PISA)
Molecular Components in 2IW8
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINEO6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
2
1
MONOTHIOGLYCEROLMONOTHIOGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303