2IC3: Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with Nonnucleoside Inhibitor HBY 097

PDB ID: 2IC3Download
MMDB ID: 43401
PDB Deposition Date: 2006/9/12
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 2IC3: dimeric; determined by author and by software (PISA)
Molecular Components in 2IC3
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H (P66 RT)
Molecule annotation
1
Reverse Transcriptase/ribonuclease H (P51 RT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
(S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE(S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303