2I03: Crystal Structure Of Human Dipeptidyl Peptidase 4 (dpp Iv) With Potent Alkynyl Cyanopyrrolidine (abt-279)

PDB ID: 2I03Download
MMDB ID: 43374
PDB Deposition Date: 2006/8/9
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2I03: dimeric; determined by author and by software (PISA)
Molecular Components in 2I03
Label Count Molecule
Proteins (2 molecules)
2
Dipeptidyl Peptidase 4
(Gene symbol: DPP4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[4-({2-[(2s,5r)-2-(Aminomethyl)-5-Ethynylpyrrolidin-1-Yl]-2-Oxoethyl}amino)-4-Methylpiperidin-1-Yl]isonicotinic Acid2-[4-({2-[(2s,5r)-2-(Aminomethyl)-5-Ethynylpyrrolidin-1-Yl]-2-Oxoethyl}amino)-4-Methylpiperidin-1-Yl]isonicotinic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303