2HV5: Human Aldose Reductase complexed with inhibitor zopolrestat after three days soaking (3days_soaked_3)

PDB ID: 2HV5Download
MMDB ID: 41708
PDB Deposition Date: 2006/7/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.59  Å
Source Organism:
Similar Structures:
Biological Unit for 2HV5: monomeric; determined by author
Molecular Components in 2HV5
Label Count Molecule
Protein (1 molecule)
1
Aldose Reductase
(Gene symbol: AKR1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303