2HFK: Pikromycin thioesterase in complex with product 10-deoxymethynolide

PDB ID: 2HFKDownload
MMDB ID: 41629
PDB Deposition Date: 2006/6/24
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.79  Å
Source Organism:
Similar Structures:
Biological Unit for 2HFK: dimeric; determined by author and by software (PISA)
Molecular Components in 2HFK
Label Count Molecule
Proteins (2 molecules)
2
Type I Polyketide Synthase Pikaiv
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
3
SULFATE IONSULFATE ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
(3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE(3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303