2H9V: Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632

PDB ID: 2H9VDownload
MMDB ID: 42834
PDB Deposition Date: 2006/6/12
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2H9V: dimeric; determined by author and by software (PISA)
Molecular Components in 2H9V
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 2
(Gene symbol: ROCK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303