2H5Z: Crystallographic Structure Of Digestive Lysozyme 1 From Musca Domestica Bound To Chitotetraose At 1.92 A Resolution

Lysozymes are mostly known for their defensive role against bacteria, but in several animals lysozymes have a digestive function. Here, the initial crystallographic characterization of two digestive lysozymes from Musca domestica are presented. The proteins were crystallized using the sitting-drop vapour-diffusion method in the presence of ammonium sulfate or PEG/2-propanol as the precipitant. X-ray diffraction data were collected to a maximum resolution of 1.9 angstroms using synchrotron radiation. The lysozyme 1 and 2 crystals belong to the monoclinic space group P2(1) (unit-cell parameters a = 36.52, b = 79.44, c = 45.20 angstroms, beta = 102.97 degrees) and the orthorhombic space group P2(1)2(1)2 (unit-cell parameters a = 73.90, b = 96.40, c = 33.27 angstroms), respectively. The crystal structures were solved by molecular replacement and structure refinement is in progress.
PDB ID: 2H5ZDownload
MMDB ID: 46173
PDB Deposition Date: 2006/5/29
Updated in MMDB: 2007/11
Experimental Method:
x-ray diffraction
Resolution: 1.92  Å
Source Organism:
Similar Structures:
Biological Unit for 2H5Z: monomeric; determined by author
Molecular Components in 2H5Z
Label Count Molecule
Protein (1 molecule)
Lysozyme 1
Molecule annotation
* Click molecule labels to explore molecular sequence information.

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